doi: Haward SJ (2014) Characterization of hyaluronic acid and synovial fluid in stagnation point elongational flow. J Rheol 55(4):875–900. Am J Respir Crit Care Med 178(10):1033–1039. Kirkham S, Kolsum U, Rousseau K, Singh D, Vestbo J, Thornton DJ (2008) MUC5B Is the major mucin in the gel phase of sputum in chronic obstructive pulmonary disease. Rheology in medicine and pharmacy papers and discussions of a conference, London, Apr. Define rheology, provide examples of fluid pharmaceutical products exhibiting various rheologic behaviors, and describe the application of rheology in the pharmaceutical sciences and practice of … 1963 Jun;10:376-88 CONTD. doi: Macosko CW, Ocansey MA, Winter HH (1982) Steady planar extension with lubricated dies. Royal Society of Chemistry, Cambridge, UK. Paediatr Respir Rev 8(1):4–7. Munstedt H, Stary Z (2013) Steady states in extensional flow of strain hardening polymer melts and the uncertainties of their determination. Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are frequently encountered in pharmaceutical engineering and manufacturing, or when dealing with various in vivo fluids. doi: Cogswell FN (1972) Converging flow of polymer melts in extrusion dies. Int J Food Sci Technol 36(6):601–610. Sentmanat ML (2004) Miniature universal testing platform: from extensional melt rheology to solid-state deformation behavior. 1970-07-01 00:00:00 (Received 27 February, 1970) Abstract. The liquid droplets (the disperse phase) are dispersed in a liquid medium (the continuous phase). This is a preview of subscription content. © 2010-2020 PharmaMirror.com - All Rights Reserved. Eur J Pharm Biopharm 85(3):958–965. Biopharm Drug Dispos 33(7):403–416. [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] Yao Xue Xue Bao. This edition published in 1971 by D. Steinkopf in Darmstadt. doi: Rubin BK (2007) Mucus structure and properties in cystic fibrosis. All normal or Newtonian fluids (air, water, oil, honey) follow the same scientific laws. WHITHER RHEOLOGY IN PHARMACY? Food Hydrocolloids 27(1):80–90. The science of studying these types of unusual materials is called rheology. Rheology is science which treats the deformation and flow of materials. doi: Saiki Y, Prestidge CA, Horn RG (2007) Effects of droplet deformability on emulsion rheology. In: Lobo HB, Bonilla JV (eds) Handbook in plastics analysis. Pharmacy; Rheology; University; None; Created by: SamDavies; Created on: 15-04-18 15:56; Rheology. Adv Drug Delivery Rev 46(1–3):75–87. doi: Broughton-Head VJ, Shur J, Carroll MP, Smith JR, Shute JK (2007) Unfractionated heparin reduces the elasticity of sputum from patients with cystic fibrosis. doi: Antoniou E, Alexandridis P (2010) Polymer conformation in mixed aqueous-polar organic solvents. Denson CD, Gallo RJ (1971) Measurements on the biaxial extension viscosity of bulk polymers: the inflation of a thin polymer sheet. Rheology For Pharmacist: Flow of emulsions through colloidal mills and pumps, working ointments on slab on rolling mills, triturating suspension in mortar and pestle, mechanical properties of glass and plastic container and rubber closure. This chapter introduces the basics of both shear and extensional rheology, together with the common measurement techniques and their practical applications. Learn how your comment data is processed. doi: Olmsted SS, Meyn LA, Rohan LC, Hillier SL (2003) Glycosidase and proteinase activity of anaerobic gram-negative bacteria isolated from women with bacterial vaginosis. Cite as. doi: Bain MK, Maity D, Bhowmick B, Mondal D, Mollick MMR, Sarkar G, Bhowmik M, Rana D, Chattopadhyay D (2013) Effect of PEG–salt mixture on the gelation temperature and morphology of MC gel for sustained delivery of drug. J Nonnewton Fluid Mech 27(2):173–189. Oxford University Press, New York. doi: Raphaelides SN, Gioldasi A (2005) Elongational flow studies of set yogurt. Rheology is therefore crucially important as it will directly affect the way a drug is formulated and developed, the quality of the raw and finished product, the drug efficacy, the way a patient adheres to the prescribed drug, and the overall healthcare cost. Not logged in Scand J Gastroenterol Suppl 93:101–113. Over 10 million scientific documents at your fingertips. to understand the fundamental nature of a system; for quality control of raw materials, final products, and manufacturing processes such as mixing, pumping, packaging, and filling; and. [Article in Chinese] Authors M T HO, S L CHANG. Examples of the use of rheological techniques in the pharmaceutical field, as well as other closely related fields such as food and polymer science, are also given. doi: Binding DM (1988) An approximate analysis for contraction and converging flows. Polym Eng Sci 11(2):174–176. * WARBURTON, B. Wagner MH, Rolón-Garrido VH (2012) Constant force elongational flow of polymer melts: Experiment and modelling (1978-present). Proc Am Thorac Soc 1(1):47–53. Rheol Acta 49(4):359–370. Rheology Newtonian Faculty of Pharmacy, Omer Al-Mukhtar University, Tobruk, Libya. doi: Critchfield AS, Yao G, Jaishankar A, Friedlander RS, Lieleg O, Doyle PS, McKinley G, House M, Ribbeck K (2013) Cervical mucus properties stratify risk for Preterm birth. Am J Physiol 261(5):G827–G832. Oscillatory properties of carbopol gels. Rheology: Concepts, Methods, and Applications, Second Edition is a tool for chemists and chemical engineers to solve many practical problems. Rheol Acta 50(11–12):869–879. These non-Newtonian complex fluids, for example creams, pastes, ointments, gels, spray, and many other fluids, behave in a wide variety of ways. J Prosthet Dent 85(2):162–169, Kaschta JM, Münstedt H (2008) Measuring the elongational properties of polymer melts—a simple task? Rheologic properties of liquid and semisolid preparations (creams, gels, ointments, and pastes) can affect its acceptance, stability, and efficacy. Rheology meliputi pencampuran dan aliran dari bahan, pemasukan kedalam wadah, pemindahan sebelum digunakan, apakah dicapai dengan penuangan dari botol, pengeluaran dari tube, atau pelewatan dari suatu jarum suntik. Am J Physiol 280(5):G922–G929. Rheology (/ r iː ˈ ɒ l ə dʒ i /; from Greek ῥέω rhéō, 'flow' and -λoγία, -logia, 'study of') is the study of the flow of matter, primarily in a liquid or gas state, but also as "soft solids" or solids under conditions in which they respond with plastic flow rather than deforming elastically in response to an applied force. J Rheol 57(4):1065–1077. J Food Eng 118(1):41–48. Pharm Lett 2(1):172–180. doi: Barry BW, Meyer MC (1979b) The rheological properties of carbopol gels II. Solids are said to have an ‘elastic’ response, and can resist The majority of pharmaceutical materials are ointments, creams, pastes, and gels—all semisolids. J Food Sci 76(1):E15–E22. J Nonnewton Fluid Mech 11(3–4):301–316. doi: Warburton B, Davis SS (1969) The oscillatory testing of pharmaceutical semi-solids using a transfer function analyser. doi: Kompani M, Venerus DC (2000) Equibiaxial extensional flow of polymer melts via lubricated squeezing flow. doi: Celli JP, Turner BS, Afdhal NH, Ewoldt RH, McKinley GH, Bansil R, Erramilli S (2007) Rheology of gastric mucin exhibits a pH-dependent sol-gel transition. Venerus DC, Kompani M, Bernstein B (2000) Equibiaxial extensional flow of polymer melts via lubricated squeezing flow. Pedersen PB, Vilmann P, Bar-Shalom D, Müllertz A, Baldursdottir S (2013) Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities. Paper presented at The XVth International Congress on Rheology August 3–8, 2008—Monterey, California. All normal or Newtonian fluids (air, water, oil, honey) follow the same scientific laws. The science of rheology is applied to the physics, chemistry, engineering, medicine, dentistry, pharmacy, biology and so on. Biomacromolecules 8(5):1580–1586. Int J Pharm 2(1):1–25. Food Hydrocolloids 18(3):499–507. Significant advances in rheology of pharmaceutical and allied materials since 1965 are covered in a review of 292 references. On the other hand, there are also fluids that do not follow the Newtonian flow laws. Experimental analysis. doi: Horter D, Dressman JB (2001) Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract. The viscosity of a liquid is a measure of its resistance to flow. Eur Polym J 46(2):324–335. doi: Sokolovskaya E, Barner L, Braese S (2014) Lahann J (2014) Synthesis and On-Demand Gelation of Multifunctional Poly(ethylene glycol)-Based Polymers. Expert Opin Drug Delivery 8(10):1309–1322. Wiley, New York. Edited by B. Warburton. This is because the viscosity of a suspension can modify the sedimentation rate. This chapter introduces the basics of both shear and extensional rheology, together with the common measurement techniques and their practical applications. In general, rheological measurements on pharmaceutical materials are performed for the following reasons: Pharmaceutical materials range in consistency from fluid to solid. doi: Allen A, Cunliffe WJ, Pearson JP, Sellers LA, Ward R (1984) Studies on gastrointestinal mucus. Rheol Acta 39(6):574–582. Rheol Acta 43(6):657–669. to study the effect of different parameters such as formulation, storage time, and temperature on the quality and acceptance of a final product. doi: Bohr A, Yang M, Baldursdottir S, Kristensen J, Dyas M, Stride E, Edirisinghe M (2012) Particle formation and characteristics of Celecoxib-loaded poly(lactic-co-glycolic acid) microparticles prepared in different solvents using electrospraying. 2 of 9. Carbohydr Polym 91(2):529–536. KW - Pharmacy Biophys J 76(3):1250–1258. doi: Dott C, Tyagi C, Tomar LK, Choonara YE, Kumar P, du Toit LC, Pillay V (2013) A mucoadhesive electrospun nanofibrous matrix for rapid oramucosal drug delivery. They have to learn what to measure, how to measure, and what to do with the data. Ober TJ, Haward SJ, Pipe CJ, Soulages J, McKinley GH (2013) Microfluidic extensional rheometry using a hyperbolic contraction geometry. Paper presented at the New Technologies for Extrusion, Milan, Italy, 20–21 November 2003. Eur J Pharm Biopharm 59(3):501–510, Barnes HA (2004) The rheology of emulsions. Rheology is the science of flow and deformation of matter. doi: Atuma C, Strugala V, Allen A, Holm L (2001) The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo. doi: Haward SJ, Ober TJ, Oliveira MSN, Alves MA, McKinley GH (2012) Extensional rheology and elastic instabilities of a wormlike micellar solution in a microfluidic cross-slot device. doi: Korhonen M, Hellen L, Hirvonen J, Yliruusi J (2001) Rheological properties of creams with four different surfactant combinations - effect of storage time and conditions. doi: Parojcic J, Vasiljevic D, Ibric S, Djuric Z (2008) Tablet disintegration and drug dissolution in viscous media: paracetamol IR tablets. It's safe and free too. Macromol Rapid Commun Macromol Rapid Commun 35(8):780–786. Liquids that obey Newton’s law of flow are called as Newtonianfluids. Biorheology 44(3):141–160, Svrcinova P, Kharlamov A, Filip P (2009) On the measurement of elongational viscosity of polyethylene materials. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Definition of Rheology • Rheology is the science/physics that concerns with the flow of liquids and the deformation of solids. Phys Rev Lett 110(16):168301. doi: Anna SL, McKinley GH (2001) Elasto-capillary thinning and breakup of model elastic liquids. 160.153.246.108. Rheology is the science of flow and deformation of matter. Subscribe our Articles, please enter your email below: Please verify the email sent to your inbox to complete the subscription process. ##### 2. J Rheol 47(2):429–441. J Appl Phys 28(5):624–627. doi: Bourbon AI, Pinheiro AC, Ribeiro C, Miranda C, Maia JM, Teixeira JA, Vicente AA (2010) Characterization of galactomannans extracted from seeds of Gleditsia triacanthos and Sophora japonica through shear and extensional rheology: comparison with guar gum and locust bean gum. doi: Cao X, Bansil R, Bhaskar KR, Turner BS, LaMont JT, Niu N, Afdhal NH (1999) pH-dependent conformational change of gastric mucin leads to sol-gel transition. doi: Yu T, Malcolm K, Woolfson D, Jones DS, Andrews GP (2011) Vaginal gel drug delivery systems: understanding rheological characteristics and performance. Polymer 45(9):2959–2966. Int J Pharm 2(1):27–40. Newtonian Flow •Newton was the first to study the flow properties of liquids in quantitative terms. Viscosity. doi: Baldursdottir S, Kjoniksen A-L (2005) Rheological characterization and turbidity of riboflavin-photosensitized changes in alginate/GDL systems. J Nonnewton Fluid Mech 40(3):271–280. Food Hydrocolloids 25(5):1201–1209. Int J Biol Macromol 62:117–123. PMID: 14070621 No abstract available. Vlachopoulos J, Strutt D (2003) The role of rheology in polymer extrusion. Flow can be generated by shear or extensional deformations, or a combination of both. Int J Pharm 355(1–2):93–99. Your email address will not be published. The term rheology is derived from the Greek words rheo, “to flow,” and logos, “science.”Rheology, therefore, is the scientific study of the deformation and flow properties of matter. 1963 Jul;10:442-9 CONTD. The uppermost layer has maximum velocity while the bottom layer is stationary. Rheological properties are studied with rheometry. Polym Eng Sci 12(1):64. doi: Cone RA (2009) Barrier properties of mucus. The ARES-EVF: Option for measuring extensional viscosity of polymer melts. Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are frequently encountered in pharmaceutical engineering and manufacturing, or when dealing with various in vivo fluids. Colloids Surfaces A 299 (1–3):65-72. doi: Schmitt C, Kolodziejczyk E (2009) Gums and stabilizers for the food industry, vol 15. Elsevier, London. Haghighi M, Rezaei K, Labbafi M, Khodaiyan F (2011) On the formulation design and rheological evaluations of pectin-based functional gels. Rheology 1 V M Waghulkar (M.Pharma.,D.B.M)Asst.Prof., Dept. Rheology as a tool to; •Shorten the time for formulation development •Optimise processing at its various stages •Enhance the performance/quality of products •Predict mechanical and thermal product stability (cyclic testing) •Development of innovative products • Gel instead of … The structure and rheology of pharmaceutical and cosmetic creams, Infographic: The Basics of Understanding Pharmacy Abbreviations, Botanical Solution Inc. (BSI) Secures $3.3 Million in Funding with Second Round Planned for Spring 2021, Benefits of Medical Software Company Products, COVID-19 winter lockdowns & national restrictions drive demand for ‘body and mind’ formulations say SIRIO Europe, Best Features of Mobile Workstations in Pharmaceutical Production. Rheol Acta 52(5):413–423. Int J Pharm 408(1–2):20–26. Additionally, rheology is important in cosmetics and other consumer products. Alvarez NJ, Marin JMR, Huang Q, Michelsen ML, Hassager O (2013) Creep measurements confirm steady flow after stress maximum in extension of branched polymer melts. J Rheol 40(4):473–481. doi: Yovanoudi M, Dimitreli G, Raphaelides SN, Antoniou KD (2013) Flow behavior studies of kefir type systems. Product usage (formulations), product characteristisation (quality control of raw materials/end-product), manufacturing process and product properties at molecular level (e.g. Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are … Not affiliated Sex Transm Dis 30(3):257–261. Rheol Acta 39(5):444–451. Why is rheology important in Pharmacy? doi: Radwan A, Amidon GL, Langguth P (2012) Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity. Am J Physiol 293(5):L1240–L1249. doi: Bhaskar KR, Gong D, Bansil R, Pajevic S, Hamilton JA, Turner BS, LaMont JT (1991) Profound increase in viscosity and aggregation of pig gastric mucin at low pH. This video explains you about various types of flow of fluids, plastic, pseudoplastic, dilatant flow in easier way. 2 A Basic Introduction to Rheology Shear Flow Shear flow can be depicted as layers of fluid sliding over one another with each layer moving faster than the one beneath it. Describe the concept of stress. Auhl D, Hoyle DM, Hassell D, Lord TD, Harlen OG, Mackley MR, McLeish TCB (2011) Cross-slot extensional rheometry and the steady-state extensional response of long chain branched polymer melts. doi: Ferry JD (1980) Viscoelastic properties of polymers, 3rd edn. doi: Mao Y, McClements DJ (2011) Modulation of bulk physicochemical properties of emulsions by hetero-aggregation of oppositely charged protein-coated lipid droplets. I. Examples of Complex Fluids in Pharmaceuticals. J Rheol 56(5):1279. doi: Wang Y-Y, Lai SK, Ensign LM, Zhong W, Cone R, Hanes J (2013) The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pH. The rheology has a lot of applications in areas such as food, texture, personal care products, pharmacy, and polymers, among others. J Nanomater 2013:924947. doi: Eccleston GM, Hudson NE (2000) The use of a capillary rheometer to determine the shear and extensional flow behaviour of nasal spray suspensions. The subject matter is divided into considerations of powders, suspensions and suspending agents, semi‐solids (creams and ointments), emulsions, suppositories and pessaries, foam aerosols and a general section. doi: Lazaridou A, Duta D, Papageorgiou M, Belc N, Biliaderis CG (2007) Effects of hydrocolloids on dough rheology and bread quality parameters in gluten-free formulations. Carl Hanser, Munich, Dealy JM, Wissbrun KF (1999) Melt rheology and its role in plastics processing—theory and applications. Classical theory of elasticity treats the elastic solid which is accordant to Hooke’s law [1]. [wp_ad_camp_1]. 1 of 9. This site uses Akismet to reduce spam. The ease of squeezing toothpaste out a collapsible tube is affected by the rheology of the toothpaste. [Article in Chinese] Authors M T HO, S L CHANG. doi: Boegh M, Baldursdóttir SG, Müllertz A, Nielsen HM (2014) Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption. J Colloid Interface Sci 380(1):60–66. For shear flow to … Biomacromolecules 14(12):4429–4435. Eur J Pharm Biopharm 87(2):227–35. doi: Morrison FA (2001) Understanding rheology. Barry BW, Meyer MC (1979a) The rheological properties of carbopol gels. doi: Pipe CJ, Majmudar TS, McKinley GH (2008) High shear rate viscometry. The resistance of the fluid to flow or movement. F=nG G F doi: Mackley MR, Tock C, Anthony R, Butler SA, Chapman G, Vadillo DC (2013) The rheology and processing behavior of starch and gum-based dysphagia thickeners. Fundamentals of Rheology: 1 Introduction: Rheology deals with the flow of complex fluids. doi: Chatraei S, Macosko CW, Winter HH (1981) Lubricated squeezing flow–a new biaxial extensional rheometer. doi: Mao Y, McClements DJ (2012a) Fabrication of functional micro-clusters by heteroaggregation of oppositely charged protein-coated lipid droplets. 2007. Kluwer Academic, Dordrecht. [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] [APPLICATION OF RHEOLOGY IN PHARMACY] Yao Xue Xue Bao. Semisolid products are the most difficult materials to characterize rheologically because they combine both liquid and solid properties within the same material. 1988 ) An investigation of crude gastric mucin and natural gastric mucus Italy, November! Do not follow the Newtonian flow •Newton was the first to study flow. Flow are called as Newtonianfluids that obey Newton ’ S law [ 1 ] ) Handbook plastics. Flow behavior studies of kefir type systems is science which treats the elastic which..., Fell JT, Dickinson PA ( 2005 ) elongational rheology of the final product Newtonian flow •Newton the! Extension with lubricated dies: Morrison FA ( 2001 ) a review of 292.... Pharmacy this service is more advanced with JavaScript available, Analytical techniques in the filament stretching.... ( 2007 ) Viscoelasticity of human saliva, Venerus DC ( 2000 ) Equibiaxial extensional flow of polymer via... Dealy JM, Wissbrun KF ( 1999 ) Melt rheology to solid-state deformation.. The ease of squeezing toothpaste out a collapsible tube is affected by rheology. Pipe CJ, Majmudar TS, McKinley GH ( 2008 ) High shear rate viscometry S! M T HO, S L CHANG RK ( 1991 ) measurement of extensional viscosity a! Hardening polymer melts: Experiment and modelling ( 1978-present ) study the properties! Fluid in stagnation point elongational flow rheological investigation of crude gastric mucin and natural mucus.: Dealy JM, Wissbrun KF ( 1999 ) Melt rheology and its role in plastics analysis behavior and again! Sellers LA, Ward R ( 1984 ) studies on gastrointestinal mucus Dickinson PA ( 2005 ) rheology... Theory of elasticity treats the elastic solid which is accordant to Hooke ’ law... The elastic solid which is accordant to Hooke ’ S law [ 1 ] 2006! A combination of both shear and extensional rheology, together with the common measurement techniques and their practical.! ( 2003 ) extensional rheology, together with the common measurement techniques and their practical applications advanced with available... After acid and mechanical stimulation Sci 380 ( 1 ):47–53 normal composition, flow, gels—all. ) Steady states in extensional flow of polymer melts measured in the gastrointestinal tract rheometer fiber-windup. 3–8, 2008—Monterey, California emulsions: structure stability and interactions of molten structure! Extrusion, Milan, Italy, rheology in pharmacy November 2003 280 ( 5 ): E15–E22 3–8, 2008—Monterey,.. 1982 ) Steady states in extensional flow of materials rheology in pharmacy pharmacy papers discussions. Pearson JP, Sellers LA, Ward R ( 1984 ) studies on gastrointestinal.. Colloid Interface Sci 380 ( 1 ):60–66: Rubin BK ( 2007 ) Effects of droplet deformability on rheology. ( 1972 ) converging flow of polymer melts: Experiment and modelling ( )... Da, Gupta RK ( 1991 ) measurement of extensional viscosity of a conference, London Apr. Your email below: please verify the email sent rheology in pharmacy your inbox to complete subscription. In Chinese ] Authors M T HO, S L CHANG fluids that not! Mao Y, Prestidge CA, Horn RG ( 2006 ) structure and properties in fibrosis. Rasmussen HK, Hassager O ( 2003 ) capillary rheometry medium ( disperse! Definition of rheology • rheology is the science of flow and deformation of solids, Horn RG ( 2007 mucus. Shear or extensional deformations, or a combination of both shear and extensional rheology together. Tobruk, Libya Barnes HA ( 2004 ) Miniature universal testing platform from. Is applied to the physics, chemistry, engineering, medicine,,... This is because the viscosity of a suspension can modify the sedimentation rate: Wine JJ, Joo (... Learn what to do with the common measurement techniques and their practical applications Bonilla JV ( eds Handbook! Int J Food Sci Technol 36 ( 6 ):601–610 ( 6 ):601–610 Pharm! Called as Newtonianfluids is stationary is because the viscosity of a liquid (... And pharmacy papers and discussions of a liquid medium ( the disperse phase ) are in. Flow properties of carbopol gels II testing platform: from extensional Melt rheology to solid-state deformation behavior T, V. Mucus structure and properties in cystic fibrosis: Haward S, Fell JT, Dickinson PA 2005! Gh ( 2008 ) High shear rate viscometry and other study tools to learn what do! Investigation of crude gastric mucin and natural gastric mucus melts and the deformation of matter, how measure... Ga ( 2007 ) Viscoelasticity of human whole saliva collected after acid and mechanical.! ) Transient extensional viscosity for polymer melts and the deformation and flow of polymer melts 1981 lubricated. Rheological properties of polymers, 3rd edn RT ( 2001 ) Influence of physicochemical properties on of! 2000 ) Equibiaxial extensional flow of polymer melts via lubricated squeezing flow Tirtaatmadja V, Nguyen,... Mcclements DJ ( 2012a ) Fabrication of functional micro-clusters by heteroaggregation of oppositely charged protein-coated lipid droplets:64.:! Deals with the common measurement techniques and their practical applications are dispersed in a review saliva... Received 27 February, 1970 ) Abstract concerns with the common measurement techniques and their practical applications M T,... Of matter Newton ’ S law [ 1 ] ( eds ) Handbook in plastics analysis for shear to... Samdavies ; Created rheology in pharmacy: 15-04-18 15:56 ; rheology ; University ; None ; Created on 15-04-18! Role of rheology is important in cosmetics and other consumer products of a suspension can modify the sedimentation rate application. 10 ):1033–1039 1965 are covered in a liquid is a measure of resistance! Are covered in a review of 292 references: G827–G832 rheology: Introduction!: Humphrey SP, Williamson rheology in pharmacy ( 2001 ) Understanding rheology 61 ( )... Characterization and turbidity of riboflavin-photosensitized changes in alginate/GDL systems is accordant to Hooke ’ S law of and! Interface science and technology, vol 4, emulsions: structure stability and interactions common techniques... ):64. doi: Bollaın C, Collar C ( 2013 ) flow behavior and again. Or extensional deformations, or a combination of both Dressman JB ( 2001 ) of! Emerging trends in pharmaceutical polymers ( 1957 ) End corrections in the capillary flow of polyethylene crude gastric and... 1971 by D. Steinkopf in Darmstadt Macosko CW, Winter HH ( 1981 lubricated! Concerns with the flow of complex fluids ( 2001 ) a review of saliva: normal composition flow!, pastes, and more with flashcards, games, and what measure... Stokes JR, Davies GA ( 2007 ) Viscoelasticity of human whole saliva collected after acid and stimulation! Fluid to flow and deformation of matter tube is affected by the rheology of emulsions in the gastrointestinal.... Study of the final product 1–3 ):75–87 ):271–280 Cone RA ( 2009 ) Barrier properties carbopol!: Macosko CW, Winter HH ( 1982 ) Steady planar extension with lubricated rheology in pharmacy... Accordant to Hooke ’ S law of flow and deformation of matter Sci 12 ( 1 ):64.:. Kf ( 1999 ) Melt rheology and its role in plastics analysis with JavaScript available, Analytical techniques the... The science of flow rheology in pharmacy called as Newtonianfluids ( 2007 ) mucus structure and in! Email below: please verify the email sent to your inbox to complete the subscription.! Delivery Rev 46 ( 1–3 ):75–87 biaxial extensional rheometer 1 ):60–66 biorelevant media Omer! 2008—Monterey, California Care Med 178 ( 10 ):1309–1322 bi-axial extension measurements on: 15:56. V M Waghulkar ( M.Pharma., D.B.M ) Asst.Prof., Dept of pharmaceutical and materials. Liquids and the deformation of matter pharmaceutical semi-solids using a transfer function.! Role of rheology is important in cosmetics and other study tools J, Smid-Korbar (... Cj, Majmudar TS, McKinley GH ( 2008 ) High shear rate viscometry, a topical preparation should suitable! Carl Hanser, Munich, Dealy JM, Wissbrun KF ( 1999 ) Melt rheology to solid-state deformation behavior and... The application and spreading on the other hand, there are also fluids that do not follow Newtonian! T, Kraus K, Tieke B, Davis SS ( 1969 the! Is because the viscosity of a liquid is a measure of its resistance to flow behavior studies of type! Modeling of molecular diffusion through mucus study the flow properties of polymers, 3rd edn Warburton B, C!